Pathogen-driven nucleotide overload triggers mitochondria-centered cell death in phagocytes.
Staphylococcus aureus is a dangerous pathogen that evolved refined immuno-evasive strategies to antagonize host immune responses.This involves the biogenesis of death-effector deoxyribonucleosides, which kill infectious foci-penetrating macrophages.However, the exact mechanisms whereby staphylococcal death-effector deoxyribonucleosides and coupled